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Undergraduate Theses

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14583/13

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Keyword: search.filters.keyword.Plant extractsSDG: search.filters.sdg.SDG 9 - Industry, innovation and infrastructure

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    A preliminary study on the average yield of crude capsaicin from common varieties of Capsicum frutescens L. at two stages (Young and mature) using three extracting solvent
    Cadornigara, Ma. Sylvia C. (Division of Physical Sciences and Mathematics, College of Arts and Sciences, University of the Philippines Visayas, 1998)
    Crude capsaicin content of the air dried and homogenized plant material of the three varieties of Capsicum frutescens L. namely cayenne, tobasco and ‘kitikot’ were determined using diethyl ether, 99.5 % ethanol and 1.0N NaOH as extracting reagents. Statistical analysis showed no significant difference on the average percent yield of crude capsaicin on the three varieties of Capsicum frutescens L. using similar extracting solvent, but a significantly higher yield of crude capsaicin was found with 99.5% ethanol and 1.0N NaOH. Through thin layer chromatography the major components of the extracts identified could probably be capsaicinoids (Rf 15-17), carotenoids (only in 99.5% ethanol, Rf 96-97), and capsanthin (Rf 27-29) using n-hexane-acetone.
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    Antidiarrheal activity of Pterocarpus indicus bark extracts using castor oil-induced diarrhea model on mice
    Cabatea, Norberto C. (Department of Chemistry, College of Arts and Sciences, University of the Philippines Visayas, 2010-04)
    This study evaluated the antidiarrheal activity of the bark of Pterocarpus indicus (Narra). The crude methanolic extract of the bark was subjected to sequential extraction using hexane, DCM, and ethyl acetate. These extracts were tested for antidiarrheal activity in vitro using the castor oil induced diarrhea model in mice employing charcoal tracing method. Thin Layer Chromatography (TLC) was used in determining the chemical constituents present in every extracts using spraying reagents to aid in the visualization of spots. Crude methanolic extract dosage 200 mg/kg body weight is the comparable dosage to the reference drug loperamide (2 mg/kg body weight). The hexane extract was the most active fraction and 200 mg/kg dosage was more effective than with the positive control loperamide (2 mg/kg). No antidiarrheal activity found in the fraction of DCM and ethyl acetate extracts. Phytochemical screening revealed positive tests for tannins, phenolics, terpenes, cardiac glycosides, saponins and reducing sugars in all fractions. Tests for flavonoids and alkaloids, however, were negative.