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Undergraduate Theses

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    Mud crab (Scylla serrata) shells for the removal of humic acids from Santa Barbara well water
    Asdillo, Reina Jean A. (Department of Chemistry, College of Arts and Sciences, University of the Philippines Visayas, 2010-04)
    The chemical contamination of drinking water from a wide range of contaminants such as humic acids can potentially lead to health-related in living organisms, especially humans. In rural areas of the Philippines, the use of low cost methods to remove water pollutants is, therefore, of great interest. In this study, osterized mud crab (Scylla serrata) shells or exoskeletons from cooked crab wastes were used to remove humic acids from the Santa Barbara well water. Adsorption experiments were done to evaluate its capacity to remove humic acids from the well water. Adsorption Isotherms and Fourier Transform Infrared Spectroscopy were employed to study the characteristics of the adsorption of humic acids onto the OSSE (osterized Scylla serrata exoskeletons). Adsorption experiments showed that at an average 1.0010 g of OSSE and after six hours of agitation, an average 74.95% of humic substances were removed from 50 mL of Montinola, Santa Barbara well water sample. Isotherm experiments showed that the experimental data can be fitted in both Langmuir and Freundlich models with low K values of 0.0235 L/mg and 0.4450 (mg/g)(L/mg), respectively. Based on the results of the above experiments, OSSE is a good adsorbent for humic acids in well waters (although more research need to be done on the removal of the substances remaining in the water after OSSE treatment) and the U-OSSE (used osterized Scylla serrata exoskeletons) can possibly be recycled.
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    Anti-inflammatory and antibacterial activities of Batuan (Garcinia binucao) fruits
    Albano, Zella Faye (Department of Chemistry, College of Arts and Sciences, University of the Philippines Visayas, 2010)
    In this study, fresh fruits of batuan (Garcinia binucao) was evaluated for its antiinflammatory and antibacterial activities. The anti-inflammatory assay using Carrageenan-Induced Paw Edema Method showed that n-hexane extracts (65.79%) and dichloromethane extracts (64.91%) exhibited anti-inflammatory activities comparable to Indomethacin, the positive control (67.11%). The antibacterial assay using Paper Disk Diffusion Method showed that crude methanolic extracts, n-hexane extracts and dichloromethane extracts at 1000pg/mL were most effective against Staphylococcus aureus. The microbial indexes were 0.39, 0.47 and 0.50 respectively. The positive control, Amoxicillin has a 3.39 microbial index. The components of the three most active extracts (crude methanolic, n-hexane and DCM extracts) from both assays were separated through Thin Layer Chromatography and subjected to phytochemical tests. Crude methanolic extracts contained alkaloids, phenolic compounds and cardiac glycosides. Both n-hexane and DCM extracts contained terpenes, alkaloids, saponins, phenolic compounds and cardiac glycosides. These bioactive compounds present may have been responsible for the antiinflammatory and antibacterial activities of the extracts.