Cuadra, Marie Johanna L.Aguila, Julex ReyBiaoco, ChristineGayatgay, Christian FaithIngalla, LydimelMacalalag, Florence MaeOmar Al-Abdalla, AfnanTolentino, Joanna RoseTorrilla, Marie Stephanie2025-06-182011-03Aguila, J. R., et al. (2011). Nasal colonization and drug-resistance patterns of Staphylococcus aureus and Staphylococcus epidermidis among young residents within the vicinity of Calajunan Dumpsite, Mandurriao, Iloilo City [Undergraduate special problem, University of the Philippines Visayas]. UPV Institutional Repository. https://hdl.handle.net/20.500.14583/249https://hdl.handle.net/20.500.14583/249Poor disposal and handling of wastes is one of the problems in developing countries as well as in urban places. Leachate, which includes potential pathogens like <i>Staphylococcus aureus</i> and <i>Staphylococcus epidermidis</i>, occurs when solid wastes adsorb moisture and may contaminate ground water sources. The increasing antibiotic resistance of these species poses a great risk to those exposed to the dumpsite. This study generally aimed to investigate nasal colonization by multidrug-resistant <i>S. aureus</i> and <i>S. epidermidis</i> in young residents of Barangay Calajunan, Mandurriao, Iloilo City and to evaluate the relationship between multidrug-resistance of <i>S. aureus</i> and <i>S. epidermidis</i> and possible risk factors such as direct exposure to the dumpsite, close contact with waste-pickers, antibiotic use, hospitalization, skin and soft-tissue infections, and personal hygiene. Nasal swabs were obtained from eighty-three young residents aged 5-14 years. Isolation and identification of <i>Staphylococcus</i> spp. were based on standard conventional biochemical methods such as mannitol fermentation, catalase and coagulase tests. Anti-staphylococcal agents for the detection of drug susceptibility patterns were penicillin G (10 units), oxacillin (1 µg), cefoxitin (30 μg), ampicillin (10 μg), vancomycin (30 μg), erythromycin (15 µg), tetracycline (30 µg), and clindamycin (2 µg). Of the fifty-one isolated presumptively identified staphylocococcal species, 92% (n=49) were identified as S. aureus and 4% (n=2) as <i>S. epidermidis</i>. The prevalence of nasal colonization of <i>S. aureus</i> and <i>S. epidermidis</i> among the study populace was 59% and 2.41%, respectively. Eighty-two percent (n=42) of the <i>S. aureus</i> isolates exhibited susceptibility to tetracycline, while 98% (n=48) exhibited resistance to ampicillin. One hundred percent (n=2) of the <i>S. epidermidis</i> isolates exhibited susceptibility to erythromycin and tetracycline, and resistance to penicillin G and ampicillin. Multidrug-resistant (MDR) strains were phenotypically determined based on non-sensitivity to two or more of the different antimicrobial classes. Sixty-one percent (n=31) of S. aureus isolates and 50% (n=2) of S. epidermidis were MDR strains. Of these staphylococcal isolates, 54.8% (n=17) were resistant to antimicrobials belonging to Penicillins and Glycopeptides with one isolate being <i>S. epidermidis</i> and 16 S. aureus. No significant association between multidrug resistance of <i>S. aureus</i> and <i>S. epidermidis</i> and the risk factors was observed among the study population (p>0.05), however, it was observed that those who bathed and washed more often were more likely to have both nasal colonization and multidrug resistance of <i>S. aureus</i> and <i>S. epidermidis.</i>viii, 79 p.Nasal colonizationDrug-resistanceStaphylococcus aureusStaphylococcus epidermidisDumpsiteLG 993.5 2011 P8 N37Staphylococcus aureusStaphylococcus epidermidisThesisNasaldrug resistancewaste disposalpathogensSDG 3 - Good health and well-beingSDG 12 - Responsible consumption and production